Don't lie down. Stand up to Chronic Migraine

BOTOX® is for adults with Chronic Migraine with 15 or more headache days a month, each lasting 4 hours or more. BOTOX® therapy is not approved for adults with migraine who have 14 or fewer headache days a month.

*BOTOX® prevents up to 9 headache days a month (vs up to 7 for placebo).

IMPORTANT SAFETY INFORMATION (continued)Back to top

Important Safety Information & Approved UseExpandCollapse

BOTOX® may cause loss of strength or general muscle weakness, vision problems, or dizziness within hours to weeks of taking BOTOX®. If this happens, do not drive a car, operate machinery, or do other dangerous activities.

Do not take BOTOX® if you: are allergic to any of the ingredients in BOTOX® (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as Myobloc® (rimabotulinumtoxinB), Dysport® (abobotulinumtoxinA), or Xeomin® (incobotulinumtoxinA); have a skin infection at the planned injection site.

The dose of BOTOX® is not the same as, or comparable to, another botulinum toxin product.

Serious and/or immediate allergic reactions have been reported. They include itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Get medical help right away if you experience symptoms; further injection of BOTOX® should be discontinued.

Tell your doctor about all your muscle or nerve conditions such as ALS or Lou Gehrig's disease, myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects including difficulty swallowing and difficulty breathing from typical doses of BOTOX®.

Tell your doctor about all your medical conditions, including if you: have or have had bleeding problems; have plans to have surgery; had surgery on your face; weakness of forehead muscles; trouble raising your eyebrows; drooping eyelids; any other abnormal facial change; are pregnant or plan to become pregnant (it is not known if BOTOX® can harm your unborn baby); are breastfeeding or plan to (it is not known if BOTOX® passes into breast milk).

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal products. Using BOTOX® with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received BOTOX® in the past.

Tell your doctor if you have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin such as Myobloc®, Dysport®, or Xeomin® in the past (tell your doctor exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; take aspirin-like products or blood thinners.

Other side effects of BOTOX® include: dry mouth, discomfort or pain at the injection site, tiredness, headache, neck pain, and eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids, swelling of your eyelids, and dry eyes.

For more information refer to the Medication Guide or talk with your doctor.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Indication
BOTOX® is a prescription medicine that is injected to prevent headaches in adults with chronic migraine who have 15 or more days each month with headache lasting 4 or more hours each day in people 18 years or older.

It is not known whether BOTOX® is safe or effective to prevent headaches in patients with migraine who have 14 or fewer headache days each month (episodic migraine).

Please see BOTOX® full Product Information including Boxed Warning and Medication Guide.

References:

  1. Natoli JL, Manack A, Dean B, Butler Q, Turkel CC, Stovner L & Lipton RB. Global prevalence of chronic migraine: a systematic review. Cephalalgia 2009.
  2. Data on file, IMS Pharmetrics + Claims Database.

Offer Statement
With the BOTOX® Savings Card you can get up to $400 off one treatment received January-March 2016 and up to $200 off per treatment for up to 4 treatments received April-December 2016 for people with Chronic Migraine. All treatments must be received within a 12-month period.

Card Usage Language
Your BOTOX® Savings Card may only be used at hospitals, physician offices, and pharmacies, and will not be accepted at any other location that normally accepts Visa® Debit cards. The BOTOX® Savings Card cannot be used at merchants outside the United States (including Internet and mail/telephone merchants).

The BOTOX® Savings Card is issued by Metropolitan Commercial Bank, member FDIC, pursuant to license by Visa U.S.A. Inc. "Metropolitan Commercial Bank" and "Metropolitan" are registered trademarks of Metropolitan Commercial Bank ©2014. See the Cardholder Agreement for Terms and Conditions. By accepting, signing, or using this savings card, you agree to the Terms and Conditions of the Cardholder Agreement. This savings card will remain the property of the issuing institution and the privilege of its use may be withdrawn at any time.

TERMS AND CONDITIONS
By participating, you understand and agree to comply with the Program rules as set forth below.

Offer is not valid for any other products or other out-of-pocket costs, even if those costs are associated with the administration of BOTOX® treatment. The BOTOX® Savings Card will be funded upon approval of claim form and EOB or SPP receipt. (If the BOTOX® prescription was filled by a Specialty Pharmacy Provider, both EOB and SPP receipt must be sent.) BOTOX® Savings Card may not be combined with any other offer or discount. This BOTOX® Savings Card is not health insurance. Patient must submit a claim form and EOB or SPP receipt within 90 days from the date of service.

Offer not valid for patients participating in Medicare, Medicaid, or any similar federal or state healthcare program, including any state medical or pharmaceutical assistance programs. If patients are eligible for drug benefits under any such program, they cannot use this BOTOX® Savings Card.

Offer void where prohibited by law, taxed, or restricted. Offer good only in the United States. Allergan, Inc., reserves the right to rescind, revoke, and amend this offer without notice.

Metropolitan Commercial Bank and Metropolitan are registered trademarks of Metropolitan Commercial Bank.
Visa is a registered trademark of Visa International Service Association.

Indication and Important Safety Information
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Taltz is a prescription medicine used to treat adults with moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet or UV light). Do not use Taltz if you have had a severe allergic reaction to ixekizumab or any of the other ingredients in Taltz.

Important Safety Information

Do not use Taltz if you have had a severe allergic reaction to ixekizumab or any of the other ingredients in Taltz. See the Medication Guide for a complete list of ingredients in Taltz. If you have a severe allergic reaction, do not take another injection of Taltz.

Taltz is a medicine that affects your immune system and may lower the ability of your immune system to fight infections. Taltz may increase your risk of infections, which can sometimes become serious.

  • Your healthcare provider (HCP) should check you for tuberculosis (TB) before you begin treatment with Taltz and may treat you for TB if you have a history of TB or have TB
  • Your HCP should watch you closely for signs and symptoms of TB during and after treatment with Taltz

Before starting Taltz, tell your HCP(s) if you

  • are being treated for an infection
  • have an infection that does not go away or that keeps coming back
  • have or have had TB, or have been in close contact with someone with TB
  • think you have an infection or have symptoms of an infection, such as
    • fever, sweats, or chills
    • muscle aches
    • cough
    • shortness of breath
    • blood in your phlegm (mucus)
    • weight loss
    • warm, red, or painful skin or sores on your body
    • diarrhea or stomach pain
    • burning when you urinate or urinating more often than usual
  • have Crohn’s disease or ulcerative colitis
  • recently received or are scheduled to receive an immunization (vaccine). People who take Taltz should not receive live vaccines. Prior to starting Taltz, consider completion of all age-appropriate immunizations according to current immunization guidelines
  • are pregnant or plan to become pregnant. It is not known if Taltz can harm your unborn baby
  • are breastfeeding or plan to breastfeed. It is not known if Taltz passes into your breast milk

After starting Taltz, call your HCP right away if you have any of the symptoms of infection listed above. Do not use Taltz if you have any symptoms of infection, unless you are instructed to by your HCP.

Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Taltz may cause serious side effects, including

  • Serious allergic reactions. Get emergency medical help right away if you get any of the following symptoms of a serious allergic reaction:
    • feeling faint
    • swelling of your face, eyelids, lips, mouth, tongue, or throat
    • trouble breathing or throat tightness
    • chest tightness
    • skin rash
  • Inflammatory bowel disease (Crohn's disease or ulcerative colitis) can happen during treatment with Taltz, including worsening symptoms. Tell your HCP if you have new or worsening symptoms of inflammatory bowel disease during treatment with Taltz, including stomach pain, diarrhea (with or without blood in stool), or weight loss

The most common side effects of Taltz include: injection site reactions, nausea, fungal infections, and upper respiratory infections. These are not all of the possible side effects of Taltz. Tell your HCP about any side effect that bothers you or that does not go away.

Call your HCP for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit fda.gov/medwatch or call 1-800-FDA-1088.

Store Taltz in the refrigerator, and protect it from light. Do not freeze Taltz or use Taltz if it has been frozen. Do not shake Taltz.

Taltz is available by prescription only.

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